works because it has been designed with an innovative IN&OUT approach, in order to take care of combination and oily skin, from inside and outside, with 3 specific and functional steps.

Next to this,  facial cleanser and cream have been formulated with the exclusive AKEOF COMPLEX, with multifactorial action and rich in natural active ingredients, which acts on multiple fronts for a final and long-term result.


Concreteness & Efficacy. This is the leitmotiv which led us to realize the 3 steps of for your daily skin routine, which guarantee you a skin visibly softier, compact and  smoothier without using many different products.

STEP: daily purifying dermo-affine cleansing 
Cleanse the face with a targeted cleanser for your type of skin is the fundamental rule for all us women (and not only!)

STEP: normalize
With 5in1 cream you find the effectiveness of 5 products, 9 vegetal extracts and a 360° action, in 1 act. It normalizes the sebum production, exfoliates and prevents the comedone formation, protects from external agents, soothes and hydrates the skin and fights against skin ageing and free radicals.

STEP: rebalance from inside
Why a food supplement? Because an action can not be definitive if it is only topical.

PLUS, food supplement, is naturally rich in Omega 3 and Omega 6 essential fatty acids in a ratio 1:3, that is the optimal ratio in order to rebalance from inside our body and to improve considerably the well-being of our skin’s cells, thanks also to the presence of Vitamin E.

3 easy steps and your skin finds its natural beauty!


The combination and oily skin and acne-prone skin can be caused by different factors and it is often difficult to understand them and to act targeted and effectively.

For this reason, we have developped the AKEOF complex that exerts a MULTIFACTORIAL GLOBAL action on the skin, thanks to the presence of natural origin extracts of Vitis vinifera seed, Oak, Camelia sinensis leaf and Vitamin E.

  • It protects and preserves the normal microbiota and its biodiversity, selectively reducing only the proliferation of acnes.
  • It creates a protective film against damages caused by air-pollutants (heavy metals, gas, pesticides) and blue light (pc, tablet, smartphone).
  • It exerts a strong antioxidant activity against free radicals.
  • It improves skin trophism thanks to the presence of essential fatty acids Omega 3 and Omega 6


is born from the inspiration, the research and the experience in women’ health of Ekuberg Pharma’s laboratories. Scientific research meets the experience of a women team that in first-hand have contributed to the development of the project.

For this reason, all products are:

  • Dermatologically tested and formulated to minimize the risk of allergies.
  • Nickel, Chrome, Cobalt, Mercury and Palladium tested (content less than 1ppm)
  • Free of ingredients of animal origin
  • Sles, Sls, paraben, thiazolinone, silicone, mineral oil free
  • Recommended also on sensitive skin

Moreover,  5in1 cream has been clinically tested on 20 women of 18-54 years with oily and combination skin. It has demonstrated visible results already in 1 week.

-35% of SEBUM 
reduction already after 7 days and
sebum-normalization after
1 month of treatment

79% of women
assess positively effectiveness
in terms of sebum-normalization
and mat effect

74% of women
assess positively
hydrating effect


The problem of combination and oily skin can affect all women, in adolescence and also in adult age and in certain periods of the life, for many factors such as hormonal unbalance, genetics or stress.

In a current scenario, where our organism has undergone multiple and continuous stress which alters its balance, such as pollution, exposure to blue light of pc and smartphone, bad diet or the frenetic lifestyle, also our skin is excessively stressed.

It is necessary to find and keep the omeostasis of the body by daily easy acts, in order to help restore the physiological function of the cells and, thus, of the skin.

With you take care of your skin and its well-being and you can find your physiological balance.